07 Abr Potent dual PPAR agonists for the treatment of metabolic and cardiovascular diseases
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[/one_fourth][three_fourth_last][box]CSIC, FIMABIS and SAS have synthesized a family of oxazolidinones which carry out a dual modulation on alpha and gamma subtypes of peroxisome proliferator-activated receptors (PPARs). These two isoforms are responsible for the concentration of circulating lipids and adipogenesis, respectively. Therefore, these compounds are particularly useful for treating metabolic and cardiovascular diseases.[/box]
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