Screening and Rational Design

COVID-19 pandemic, a massive global health crisis, has fostered the implication of international research groups seeking for a solution. The peptidomimetics group has started a research line focused in the search of new antivirals. Two alternative strategies are being followed: 1) High through put screening of in-house collection, that have allowed the identification of interesting compounds with antiviral activity against SARS-CoV-2, 2) Rational design on the base of the structure of SARS-CoV-2 Main Protease (MPro)