por jap | Ago 22, 2016 | Collaborations
Biological studies – The group of Prof. I. Martín-Fontelles (URJ) is a reference group in the study of the cannabinoid system with a wide experience in various aspects of biological research as reflected in its publications on topics such as pain, cardiovascular...
por jap | Ago 22, 2016 | Drugs Against Chagas Disease
Currently, the only approved therapeutics for the treatment of Chagas disease are two nitroheterocyclic compounds, a nitrofuran (nifurtimox; Lampit) and a nitroimidazole (benznidazol; Rochagan) although in the United States these drugs are not approved by FDA (Food...
por jap | Ago 22, 2016 | Cannabinoid Receptors
As a first work in the cannabinoid field we carried out a modeling study of CBRs, using the X-ray structure of bovine Rodopsine (pdb code: 1f88) as structural template. Docking studies with the most representative cannabinoids, described as partial agonists or...
por jap | Ago 22, 2016 | Trypanosoma cruzi
An infected triatomine insect vector takes a blood meal and releases trypomastigotes in its feces near the site of the bite wound. After metacyclic trypomastigotes pass through the skin, they briefly travel in the blood stream and then colonize muscle and neuron...
por jap | Ago 22, 2016 | The Parasite: Trypanosoma Cruzi
Trypanosoma cruzi belongs to the subkingdom Protozoa and to the subspecies A. stercoria, because the parasite develops its infectious stage in the insect’s digestive tract. They are flagellar organisms that have one nucleus and an organelle, the kinetoplast,...
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