Publicaciones anteriores a 2015
- «Involvement of central and peripheral cannabinoid receptors on antinociceptive effect of tetrahydrocannabinol in muscle pain» Bagüés, A.; Martín, M. I.; Sánchez-Robles, E. M.
Eur. J. Pharmacol, 2014, 745, 69-75 (ir a revista) - «Effects of Cl888 on Kv4.3, Kv4.3/Kchip2C and Kv4.3/KChiP3 Channels»
Prieto A.; Cercos P.; de la Cruz A.; González T.; Gutierrez-Rodriguez M.; Naranjo J.R.; Valenzuela C. Biophys. J., 2014, 106, p544a (ir a revista) - «Enantioselective synthesis of PPAR agonists and antagonists» P. Goya, R. Fernández, R. González-Muñiz, J. Elguero. Curr. Top. Med. Chem., 2014, 14, 1283-1293
- «Clicked bis-PEG-peptide conjugates for studying calmodulin-Kv7.2 channel binding»
Bonache, MA; Alaimo, A; Malo, C; Millet, O; Villarroel, A; Gonzalez-Muniz, R
ORGANIC & BIOMOLECULAR CHEMISTRY, 2014, 12, 8877-8887 (ir a revista) - «Chalcones as positive allosteric modulators of alpha 7 nicotinic acetylcholine receptors: A new target for a privileged structure» Balsera, B; Mulet, J; Fernandez-Carvajal, A; de la Torre-Martinez, R; Ferrer-Montiel, A; Hernandez-Jimenez, JG; Estevez-Herrera, J; Borges, R; Freitas, AE; Lopez, MG; Garcia-Lopez, MT; Gonzalez-Muniz, R; de Vega, MJP; Valor, LM; Svobodova, L; Sala, S; Sala, F; Criado, M EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 86, 724-739 (ir a revista)
- «De Novo Designed Library of Linear Helical Peptides: An Exploratory Tool in the Discovery of Protein-Protein Interaction Modulators» Bonache, MA; Balsera, B; Lopez-Mendez, B; Millet, O; Brancaccio, D; Gomez-Monterrey, I; Carotenuto, A; Pavone, LM; Reille-Seroussi, M; Gagey-Eilstein, N; Vidal, M; de la Torre-Martinez, R; Fernandez-Carvajal, A; Ferrer-Montiel, A; Garcia-Lopez, MT; Martin-Martinez, M; de Vega, MJP; Gonzalez-Muniz, R ACS COMBINATORIAL SCIENCE, 2014, 16, 250-258 (ir a revista)
- «Chameleonic reactivity of α-amino nitrile-derived ureas. Synthesis of highly functionalized imidazolidin-2-one and imidazolidine-2,4-dione derivatives» Ventosa-Andres, P; Gonzalez-Vera, JA; García-Lopez, MT: Herranz, R Tetrahedron, 2014, 55, 2142-2145
- «Tetramic acids and indole derivatives from amino acid b-keto esters. Fine-tuning the conditions of the key Cu-catalyzed reaction» Garcia-Aranda, MI; Garcia-Lopez, MT; de Vega, MJP; Gonzalez-Muniz, R Tetrahedron Lett., 2014, 55, 2142-2145 (ir a revista)
- «Exploring the Phe-Gly Dipeptide-Derived Piperazinone Scaffold in the Search for Antagonists of the Thrombin Receptor PAR1.» Valdivielso, AM; Garcia-Lopez, MT; Gutierrez-Rodriguez, M; Herranz, R Molecules (Basel, Switzerland), 2014, 19, 4814-46 (ir a revista)
- «An Update on the Synthesis of β-Lactams» M.T. Aranda, P. Pérez-Faginas, R. González-Muñiz. Advances in Organic Synthesis (eBook, Bentham), 2013, 6, 296-354
- «Highly functionalized 2-oxopiperazine-based peptidomimetics: An approach to PAR1 antagonists» Valdivielso, AM; Ventosa-Andres, P; Tato, F; Fernandez-Ibanez, MA; Pappos, I; Tsopanoglou, NE; Garcia-Lopez, MT; Gutierrez-Rodriguez, M; Herranz, R EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 70, 199-224 (ir a revista)
- «The Parkinson´s disease-associated GPR37 receptor-mediated cytotoxicity is controlled by its intracellular cysteine-rich domain» Gandia, J; Fernandez-Duenas, V; Morato, X; Caltabiano, G; Gonzalez-Muniz, R; Pardo, L; Stagljar, I; Ciruela, F JOURNAL OF NEUROCHEMISTRY, 2013, 125, 362-372 (ir a revista)
- «Helical peptides from VEGF and Vammin hotspots for modulating the VEGF-VEGFR interaction» Garcia-Aranda, MI; Gonzalez-Lopez, S; Santiveri, CM; Gagey-Eilstein, N; Reille-Seroussi, M; Martin-Martinez, M; Inguimbert, N; Vidal, M; Garcia-Lopez, MT; Jimenez, MA; Gonzalez-Muniz, R; de Vega, MJP ORGANIC & BIOMOLECULAR CHEMISTRY, 2013, 11, 1896-1905 (ir a revista)
- «Solvent-Free Synthesis of alpha-Amino Nitrile-Derived Ureas»
Ventosa-Andres, P; Gonzalez-Vera, JA; Garcia-Lopez, MT; Herranz, R
ORGANIC LETTERS, 2013, 15, 632-635 (ir a revista) - «Synthesis and Regioselective Functionalization of Piperazin-2-ones Based on Phe-Gly Pseudodipeptides» Angel M. Valdivielso, Pilar Ventosa-Andrés, M. Teresa García-López, Rosario Herranz, and Marta Gutiérrez-Rodríguez Eur J Org Chem, 2013, 1, 155-161 (ir a revista)
- «Highly Functionalized 1,2-Diamino Compounds through Reductive Amination of Amino Acid-Derived beta-Keto Esters.» Perez-Faginas, P; Aranda, M T; Garcia-Lopez, M T; Infantes, L; Fernandez-Carvajal, A; Gonzalez-Ros, J M; Ferrer-Montiel, A; Gonzalez-Muniz, R
PloS one, 2013, 8, e53231 (ir a revista) - «A study on the induction of stereoselectivity in the Strecker synthesis of basic amino acid-derived alpha-amino nitriles» Ventosa-Andres, P; Garcia-Lopez, MT; Herranz, R
Tetrahedron-Asymmetry, 2012, 23, 15-16 (ir a revista) - «Advances in modulating thermosensory TRP channels» Ferrer-Montiel, A; Fernandez-Carvajal, A; Planells-Cases, R; Fernandez-Ballester, G; Gonzalez-Ros, JM; Messeguer, A; Gonzalez-Muniz, R. Expert Oppinion on Therapeutic Patents, 2012, 22, 999-1017 (ir a revista)
- «Azepane Quaternary Amino Acids As Effective Inducers of 3(10) Helix Conformations» Nunez-Villanueva, D; Infantes, L; Garcia-Lopez, MT; Gonzalez-Muniz, R; Martin-Martinez, M. Journal of Organic Chemistry, 2012, 77, 9833-9839 (ir a revista)
- «Design, synthesis and biological evaluation of new peptide-based ureas and thioureas as potential antagonists of the thrombin receptor PAR1.» Ventosa-Andres, P; Valdivielso, A M; Pappos, I; Garcia-Lopez, M T; Tsopanoglou, N E; Herranz, R
European Journal of Medicinal Chemistry, 2012, 58, 98-111 (ir a revista) - «Discovery of new hits for TRPV1 blockade by high throughput assays» Martinez, RD; Fernandez-Carvajal, A; Aranda, MT; Perez-Faginas, P; Bonache, MA; Gonzalez-Muniz, R; Ferrer-Montiel, A. Febs Journal, 2012, 279, 108-108 ISSN: 1742-464X
- «Cyclic amino acid linkers stabilizing key loops of brain derived neurotrophic factor»
Baeza, JL; de la Torre, BG ; Santiveri, CM; Almeida, RD; Garcia-Lopez, MT; Gerona-Navarro, G; Jaffrey, SR; Jimenez, MA; Andreu, D; Gonzalez-Muniz, R; Martin-Martinez, M
Bioorganic & Medicinal Chemistry Letters, 2012, 22, 444-448 (ir a revista) - «Optically active 1,3,4,4-tetrasubstituted beta-lactams: Synthesis and evaluation as tumor cell growth inhibitors» Perez-Faginas, P; Aranda, MT; Garcia-Lopez, MT; Francesch, A; Cuevas, C; Gonzalez-Muniz, R EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 46, 5108-5119 (ir a revista)
- «Disulfide and amide-bridged cyclic peptide analogues of the VEGF(81-91) fragment: Synthesis, conformational analysis and biological evaluation» Garcia-Aranda, MI; Mirassou, Y; Gautier, B; Martin-Martinez, M; Inguimbert, N; Vidal, M; Garcia-Lopez, MT; Jimenez, MA; Gonzalez-Muniz, R; de Vega, MJP
BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 19, 7526-7533 (ir a revista) - «Synthesis and SAR studies on azetidine-containing dipeptides as HCMV inhibitors»
Perez-Faginas, P; Aranda, MT; Garcia-Lopez, MT; Snoeck, R; Andrei, G; Balzarini, J; Gonzalez-Muniz, R. BIOORGANIC & MEDICINAL CHEMISTRY , 2011, 19, 1155-1161 (ir a revista) - «Parallel solid-phase synthesis of a small library of linear and hydrocarbon-bridged analogues of VEGF(81-91): Potential biological tools for studying the VEGF/VEGFR-1 interaction» Garcia-Aranda, MI; Marrero, P; Gautier, B; Martin-Martinez, M; Inguimbert, N; Vidal, M; Garcia-Lopez, MT; Jimenez, MA; Gonzalez-Muniz, R; de Vega, MJP
BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 19, 1978-1986 (ir a revista) - «TRPV1 modulators: Structure-activity relationships using a rational combinatorial approach» Zaccaro, L; Garcia-Lopez, MT; Gonzalez-Muniz, R; Garcia-Martinez, C; Ferrer-Montiel, A; Albericio, F; Royo, M BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 21, 3541-3545 (ir a revista)
- «Helical peptides derived from the dimerization helix of the capsid protein of HIV-1bind protein wt. Domenech, R; Bocanegra, R; Gonzalez-Muniz, R; Gomez, J; Mateu, MG; Neira, JL
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2011, 40, 137-137 IDS Number: 804EO ISSN: 0175-7571 - «Quaternary alpha,alpha-2-Oxoazepane alpha-Amino Acids: Synthesis from Ornithine-Derived beta-Lactams and Incorporation into Model Dipeptides»
Nunez-Villanueva, D; Bonache, MA; Infantes, L; Garcia-Lopez, MT; Martin-Martinez, M; Gonzalez-Muniz, R. JOURNAL OF ORGANIC CHEMISTRY, 2011, 76, 6592-6603 (ir a revista) - «A Role for Ring-Closing Metathesis in Medicinal Chemistry: Mimicking Secondary Architectures in Bioactive Peptides» de Vega, MJP; Garcia-Aranda, MI; Gonzalez-Muniz, R
MEDICINAL RESEARCH REVIEWS, 2011, 31, 677-715 (ir a revista) - «Larger Helical Populations in Peptides Derived from the Dimerization Helix of the Capsid Protein of HIV-1 Results in Peptide Binding toward Regions Other than the «Hotspot» Interface» Domenech, R; Bocanegra, R; Gonzalez-Muniz, R; Gomez, J; Mateu, MG; Neira, JL
BIOMACROMOLECULES, 2011, 12, 3252-3264 (ir a revista) - «Solid-Phase Synthesis of a Library of Amphipatic Hydantoins. Discovery of New Hits for TRPV1 Blockade» Gerona-Navarro, G; Gonzalez-Muniz, R; Fernandez-Carvajal, A; Gonzalez-Ros, JM; Ferrer-Montiel, A; Carreno, C; Albericio, F; Royo, M
ACS COMBINATORIAL SCIENCE, 2011, 13, 458-465 (ir a revista) - «Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers» de Vega MJP, Garcia-Lopez MT, Zaccaro L, Royo M, Albericio F, Fernandez-Carvajal A, Ferrer-Montiel A, Gonzalez-Muniz R
MOLECULES, 2010, 15, 4924-4933 (ir a revista) - «2-Alkyl-2-carboxyazetidines as gamma-turn inducers: incorporation into neurotrophin fragments» Baeza JL, Bonache MA, Garcia-Lopez MT, Gonzalez-Muniz R, Martin-Martinez M
AMINO ACIDS, 2010, 39, 1299-1307 (ir a revista) - «Induction Of A Gamma-Turn In 26rfa And 26rfa(20-26) by Insertion Of Azetidine-Derived Amino Acids» Lefranc LB, Neveu C, Baeza JL, Gonzalez-Muniz R , Le Marec O , Guilhaudis L, Segalas-Milazzo I , Vaudry H, Martn-Martinez M, Leprince J
JOURNAL OF PEPTIDE SCIENCE, 2010, 16, 99-99 ISSN: 1075-2617. - «Thrombin-Activated Receptors: Promising Targets for Cancer Therapy?» Garcia-Lopez MT, Gutierrez-Rodriguez M, Herranz R CURRENT MEDICINAL CHEMISTRY, 2010, 17, 109-128 ISSN: 0929-8673.
- «Further Evidence for 2-Alkyl-2-carboxyazetidines as γ-Turn Inducers» J. L. Baeza, G. Gerona-Navarro, K. Thompson; M. J. Pérez de Vega, L. Infantes; M. T. García-López, R. González-Muñiz, M. Martín-Martínez. J. Org. Chem., 2009, 74, 8203-8211
- «An update on the synthesis of ß–lactams.» Aranda, M. T.; Pérez-Faginas, P.; González-Muñiz, R. Curr. Org. Synth, 2009, 6, 325-341 (ir a revista)
- «Disulfide bonds versus Trp…Trp pairs in non-regular ß-hairpins: NMR structure of Vammin loop 3-derived peptides as a case study.» Mirasou, Y; Santiveri, C. M.; Pérez de Vega, M. J.; González-Muñiz, R.; Jiménez, M. J. ChemBioChem, 2009, 10, 902-910 (ir a revista)
- «Diimine reduction of C=C double bonds: Scope and limitations of the application to solid-phase peptide synthesis.» García-Aranda, M. I.; González-Muñiz, R.; García-López, M. T.; Pérez de Vega, M. J. Eur. J. Org. Chem. , 2009, 0, 4149-4157 (ir a revista)
- «The N-terminal tripeptide of insulin-like growth factor-I protects against beta-amyloid-induced somatostatin depletion by calcium and glycogen synthase kinase 3 beta modulation.» Burgos-Ramos, E.; Martos-Moreno, G. A.; López, M. G.; Herranz, R.; Aguado-Llera, D.; Egea, J.; Frechilla, D.; Cenarruzabeitia, E.; León, R.; Arilla-Ferreiro, E.; Argente, J.; Barrios, V J Neurochem. , 2009, 109, 360-70 (ir a revista)
- «Improved synthesis of the PAR-1 thrombin receptor antagonist RWJ-58259.»
Valdivielso, A. M.; García-López, M. T.; Herranz, R. ARKIVOC, 2008, 0, 287-294 (08-3630JP). - «Simple, highly enantioselective access to quaternary 1,3,4,4-Ttetrasubstituted ß-lactams from amino acids: A solid-phase approach,» Pérez-Faginas, P.; Aranda, M. T.; Coady, L.; García-López, M. T. and González-Muñiz, R. Adv. Synth. Catal. , 2008, 350, 2279-2285 (ir a revista).
- «Synthesis and antitumoral evaluation of indole alkaloid analogues containing an hexahydropyrrolo[1´, 2´,3´:1, 9a, 9]imidazo[1, 2-a]indole skeleton.»
Ventosa Andrés, P.; González-Vera, J. A.; Valdivielso, A. M.; García-López, M. T. and Herranz, R. Bioorg. Med. Chem. , 2008, 16, 9313-9322 PMID: 18818089 - «Potential of amino acid derived alfa-amino nitriles for generating molecular diversity.»
González-Vera, J. A.; García-López, M. T. and Herranz, R. Mini-Rev. Org. Chem. , 2008, 5, 209-221 (ir a revista) - «Exploring the binding pocket for pyridopyrimidine ligands at the CCK1 receptor by molecular docking,» Toumi-Maouche, A.; Maouche, B.; Taïri-Kellou, S.; El-Aoufi, S.; Martín-Martínez, M.; González-Muñiz, R.; Fourmy, D. and Maigret, M.
J. Mol. Model , 2008, 14, 303–314 PMID: 18286312«Synthesis and biological properties of ß-turned Aß31-35 constrained analogues.» Pérez de Vega, M. J.; Baeza, J. L.; García-López, M. T.; Vila-Perelló, M.; Jiménez-Castells, C.; Simón, A. M.; Frechilla, D.; Del Río, J.; Gutiérrez-Gallego, R.; Andreu, D. and González-Muñiz, R.
Bioorg. Med. Chem. Lett. , 2008, 18, 2078-2082 PMID: 18262786. - «Azetidine-derived amino acids versus proline derivatives. Alternative trends in reverse turn inductions.» Baeza, J. L., Gerona-Navarro, G., Pérez de Vega, M. J., García-López, M. T., González-Muñiz, R. and Martín-Martínez, M. J. Org. Chem. , 2008, 73, 1704-1715 PMID: 18217770.
- «From theoretical calculations to the enantioselective synthesis of a 1,3,4-trisubstituted Gly-derived 2-azetidinone» Pérez-Faginas, P.; Alkorta, I.; García-López, M. T. and González-Muñiz, R.Tetrahedron Lett. , 2008, 49, 215-218 (ir a revista)
- «A microarray strategy for mapping of Protein Tyrosine Phosphatase Substrate Specificity.» Köhn, M.; Gutierrez-Rodriguez, M.; Jonkheijm, P.; Wetzel, S.; Wacker, R.; Schröder, H.; Prinz, H.; Niemeyer, C.M.; Breinbauer, R.; Szedlacsek, S. E.; Waldmann, H.
Angew. Chem. Int. Ed.,, 2007, 46, 7700-7703 (ir a revista) - «Exploiting the Substrate Tolerance of Farnesyltransferase for Site-Selective Protein Derivatization.» Nguyen, U. T. T.; Cramer, J.; Gomis, J.; Reents, R.; Gutierrez-Rodriguez, M.; Goody, R. S.; Alexandrov, K.; Waldmann, H. ChemBioChem,, 2007, 8, 408-423 (ir a revista)
- «Modulation of protein-protein interactions by stabilizing/mimicking protein secondary structure elements.» Pérez de Vega, M. J.; Martín-Martínez, M.; González-Muñiz, R.
Curr. Top. Med. Chem. , 2007, 7, 33-62 PMID: 17266595. - «Synthesis of indole alkaloid analogues containing the novel hexahydropyrrolo [10,20,30:1,9a,9]imidazo[1,2-a]indole skeleton by ring-closing reactions of tryptophan-derived alfa-amino nitriles.» González-Vera, J. A.; García-López, M. T. and Herranz, R.
Tetrahedron, 2007, 63, 9229-9234 (ir a revista) - «Strategies for the design of non peptide CCK1R agonist/antagonist ligands.»
García-López, M. T.; González-Muñiz, R.; M.Martín-Martínez and R.Herranz
Curr. Top. Med. Chem. , 2007, 7, 1180-1194 PMID: 17584140«Synthesis of indole alkaloid analogues: Novel domino stereoselective electrophile addition-cyclization of tryptophan-derived alfa-amino nitriles.»
González-Vera, J. A.; García-López, M. T. and Herranz, R.
J. Org. Chem. , 2007, 72, 5395-5398 PMDI: 17579457«2-Alkyl-2-carboxyazetidines as scaffolds for the induction of beta-turns.» Baeza, J. L.; Gerona-Navarro, G.; Pérez de Vega, M. J.; García-López, M. T.; González-Muñiz, R. and Martín-Martínez, M.
Tetrahedron Lett. , 2007, 48, 3689-3693 (ir a revista) - «Exceptional Stereoselectivity in the Synthesis of 1,3,4-Trisubstituted 4-Carboxy -ß-Lactam Derivatives from Amino Acids.» Pérez-Faginas, P.; O Reilly, F.; O Byrne, A.; García-Aparicio, C.; Martín-Martínez, M.; Pérez de Vega, M. J.; García-López, M. T. and González-Muñiz, R. Org. Lett. , 2007, 9, 1593-1597 PMID: 17381101
- «Chiral 1,3,6-trisubstituted tetrahydropyrimidine-2,4-diones: A convenient stereoselective synthesis from aspartic acid derivatives.» Patiño-Molina, R.; Cubero-Lajo, I.; Pérez de Vega, M. J.; García-López, M. T. and González-Muñiz, R. Tetrahedron. Lett. , 2007, 48, 3613-3616 (ir a revista)
- «Simple approach to highly functionalized tetrahydropyrimidine-2,4-diones from perhydropyrazino[1,2-f]pyrimidine-3,6,8-trione precursors» Patiño-Molina R.; García-López, M. T.; Cenarruzabeitia, E.; Del Río, J. and González-Muñiz, R.
Synthesis, , 2007, 0, 1047-1053 (ir a revista) - «Studies on the reduction and reductive alkylation of amino-acid derived spirocyclic 2,6-dioxopiperazines.» González-Vera, J. A.; Ventosa-Andrés, P.; Cassey, J.; García-López, M. T. and Herranz, R. Tetrahedron,, 2007, 63, 2675-2683 (ir a revista)
- «Regioselective Base-promoted nucleophilic ring opening of spirocyclic 2,6-dioxopiperazines: Synthesis, of N-(1-carboxycyclohexyl)amino acid derivatives.»
González-Vera, J. A.; García-López, M. T. and Herranz, R
Eur. J. Org. Chem, 2007, 0, 548-554 (ir a revista) - «A generic building block for C- and N-terminal protein-labeling and protein-immobilization.» Watzke, A.; Gutierrez-Rodriguez, M.; Köhn, M.; Wacker, R.; Schröder, H.; Breinbauer, R.; Kuhlmann, J.; Alexandrov, K.; Niemeyer, C. M.; Goody , R. S.; Waldmann, H..
Bioorg. Med. Chem., 2006, 14, 6288-6306 (ir a revista) - «Site-Selective Protein-Immobilization by Staudinger Ligation.»
Watzke, A.; Köhn, M.; Gutierrez-Rodriguez, M.; Wacker, R.; Schröder, H.; Breinbauer, R.; Kuhlmann, J.; Alexandrov, K.; Niemeyer, C. M.; Goody , R. S.; Waldmann, H.
Angew. Chem. Int. Ed., , 2006, 45, 1408-1412 (ir a revista) - «ß-Lactams derived from phenylalanine and homologues: effects of the distance between the aromatic ring and the alfa-strogenic reactive center on the memory of chirality.»
Bonache, M. A.; Cativiela, C.; García-Lopez, M. T. and González-Muñiz, R.
Tetrahedron. Lett. , 2006, 47, 5883-5887 (ir a revista) - «The neuroprotective activity of GPE tripeptide analogues does not correlate with glutamate receptor binding affinity.» Alonso de Diego, S. A.; Gutierrez-Rodriguez, M.; Pérez de Vega, M. J.; González-Muñiz, R.; Herranz, R.; Martín-Martínez, M.; Cenarruzabeitia, E.; Frechilla, D.; Del Río, J.; Jimeno, M. L. and García-López, M. T. Bioorg. Med. Chem. Lett. , 2006, 16, 3396-3400 PMDI: 16650992
- «Old molecules for new receptors: Trp(Nps)dipeptide derivatives as vanilloid TRPV1 channel blockers.» Bonache, M. A.; García-Martínez, C.; García de Diego, L.; Carreño, C.; Pérez de Vega, M. J.; García-López, M. T.; Ferrer-Montiel, A. and González-Muñiz, R.
ChemMedChem, 2006, 1, 429-438 PMID: 16892378 - «New (Gly-Pro-Glu) (GPE) analogues. Expedite solid-phase synthesis and biological activity.» Alonso de Diego, S. A.; Gutierrez-Rodriguez, M.; Pérez de Vega, M. J.; Casabona, D.; Cativiela, C.; González-Muñiz, R.; Herranz, R.; Martín-Martínez, M.; Cenarruzabeitia, E.; Frechilla, D.; Del Río, J.; Jimeno, M. L. and García-Lopez, M. T. Bioorg. Med. Chem. Lett. , 2006, 16, 1392-1396 PMID: 16321525
- «Stereoselective synthesis of amino acid-derived ß-lactams. Experimental evidence for TADDOL as a memory of chirality enhancer.» Bonache, M. A.; López, P.; Martín-Martínez, M.; García-López, M.T.; Cativiela, C. and González-Muñiz, R. Tetrahedron, 2006, 62, 130-138 (ir a revista)
- «New TRPV1 targeting agents for pain management.» González-Muñiz, R.
Drug Discov. Today , 2005, 10, 1704-1705 PII: S1359-6446(05)03677-9 - «Conformationally constrained CCK4 analogues incorporating IBTM and BTD ß-turn mimetics» Martín-Martínez, M.; De la Figuera, N.; Latorre, M.; García-López, M. T.; Cenarruzabeitia, E.; Del Río, J. and González-Muñiz, R. J. Med. Chem. , 2005, 48, 7667-674 PMID: 16302807
- «Novel domino cyclization of tryptophan-derived amino nitriles. Scope and stereoselectivity.» González-Vera, J. A.; García-López, M. T. and Herranz, R. J. Org. Chem. , 2005, 70, 8971-8976 PMID: 16049195
- «Combination of molecular modeling, site-directed mutagenesis and SAR studies to delineate the binding site of pyridopyrimidine antagonists of the human CCK1 receptor.» Martín-Martínez, M.; Marty, A.; Jourdan, M.; Escrieut, C.; Archer, E.; González-Muñiz, R.; García-López, M. T.; Maigret, B.; Herranz, R. and Fourmy, D. J. Med. Chem. , 2005, 48, 4842-4850 PMID: 16033264
- «Analogues of the neuroprotective tripeptide Gly-Pro-Glu (GPE). Synthesis and structure-activity relationships.» Alonso de Diego, S. A.; Muñoz, P.; González-Muñiz, R.; Herranz, R.; Martín-Martínez, M.; Cenarruzabeitia, E.; Frechilla, D.; Del Río, J.; Jimeno, M. L. and García-López, M.T. Bioorg. Med. Chem. Lett. , 2005, 15, 2279-2283 PMID: 15837309
- «Molecular diversity via amino acid derived alfa-amino nitriles: Synthesis of spirocyclic 2,6-dioxopiperazine derivatives.» González-Vera, J. A.; García-López, M. T. and Herranz, R.
J. Org. Chem. , 2005, 70, 3660-3666 PMID: 15845004 - «From 1-acyl- ß lactam human cytomegalovirus protease inhibitors to 1-benzyloxycarbonylazetidines with improved antiviral activity. A straightforward approach to covalent to noncovalent inhibitors.» Gerona-Navarro, G.; Pérez de Vega, M. J.; García-López, M.T.; Andrei, G.; Snoeck, R.; Balzarini, J.; De Clercq, E. and González-Muñiz, R.
J. Med. Chem. , 2005, 48, 2612-2621 PMID: 15801851 - «Synthesis, conformational analysis and cytotoxicity of conformationally constrained Aplidine and Tamandarine A analogues incorporating a beta-turn mimetic.»
Gutierrez-Rodríguez, M.; Martín-Martínez, M.; García-López, M. T.; Herranz, R.; Polanco, C.; Cuevas, F.; Rodríguez-Campos, I.; Manzanares, I.; Cárdenas, F.; Feliz, M.; Lloyd-Williams, P. and Giralt, E. J. Med. Chem. , 2004, 47, 5700-5712 PMID: 15509169 - «Thiourea-based potent and selective HCMV inhibitors»
González-Muñiz, R Drug Discov. Today , 2004, 9, 1081-1082 PII: S1359-6446(04)03264-7 - «5-(Tryptophylamino)-1,3-dioxoperhydro[1,2-c]pyrimidine-based potent and selective CCK1 receptor antagonists: Reversal of CCK1 receptor subtype selectivity toward CCK2 receptors.» Muñoz-Ruiz, P.; García-López, M. T.; Cenarruzabeitia, E.; Del Río, J.; Dufresne, M.; Foucaud, M.; Fourmy, D. and Herranz, R
J. Med. Chem. , 2004, 47, 5318-5329 PMID: 15456276 - «Unprecedent stereospecific synthesis of a novel tetracyclic ring system, a hybrid of tetrahydropyrrolo[2,3-b]indole and tetrahydroimidazo[1,2-a]indole, via a domino reaction upon a tryptophan-derived amino nitrile.» González-Vera, J. A.; García-López, M. T. and Herranz, R. Org. Lett. , 2004, 6, 2641-2644 PMID: 15281733
- «Gly-Pro-Glu protects ß-amyloid-induced somatostatin depletion in the rat cortex»
Aguado-Llera, D.; Martín-Martínez, M.; García-López, M. T.; Arilla-Ferreiro, E. and Barrios, V.
NeuroReport, 2004, 15, 1979-1982 PMID: 15305149 - «Dipeptoids: From the chemical structure of the endogenous peptide to the design of peptidomimetics.» Martín-Martínez, M.; Patiño-Molina, R.; García-López, M.T. and González-Muñiz, R. Mini Reviews Med. Chem, 2004, 4, 669-680 PMID: 15279601
- «Pharmacological study of IQM-97,423, a potent and selective CCK1 antagonist with protective effect in acute pancreatitis.» Latorre, M.; Bartolomé-Nebreda, J. M.; García-López, M.T.; González-Muñiz, R., Herranz, R.; Del Río, J. and Cenarruzabeitia, E.
Pharmacology, 2004, 72, 68-76 PMID: 15331911 - «Improved synthesis of [4,4]spirolactam beta-turn mimetic as surrogate of the didemnin side chain dipeptide Pro-N-Me-D-Leu.» Gutierrez-Rodríguez, M.; García-López, M. T. and Herranz, R. Tetrahedron, 2004, 60, 5177-5183 (ir a revista)
- «Synthesis and anti-HCMV activity of 1-acyl-ß-lactams and 1-acylazetidines derived from phenylalanine.» Gerona-Navarro, G.; Pérez de Vega, M. J. ; García-López, M.T.; Andrei, G.; Snoeck, R.; Balzarini, J.; De Clercq, E. and González-Muñiz, R. Bioorg. Med. Chem. Lett. , 2004, 14, 2253-2256 PMID: 15081019
- «Simple access to novel azetidine-containing conformationally restricted amino acids by chemoselective reduction of beta-lactams.» Gerona-Navarro, G.; Bonache, M. A.; Alias, M.; Pérez de Vega, M. J.; García-López, M. T.; López, P.; Cativiela, C. and González-Muñiz, R. Tetrahedron Lett, 2004, 45, 2193-2196 (ir a revista) tetlet.2004.01.023
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