Publicaciones anteriores a 2015

  •  «Involvement of central and peripheral cannabinoid receptors on antinociceptive effect of tetrahydrocannabinol in muscle pain»  Bagüés, A.; Martín, M. I.; Sánchez-Robles, E. M.
    Eur. J. Pharmacol2014745, 69-75  (ir a revista)
  • «Effects of Cl888 on Kv4.3, Kv4.3/Kchip2C and Kv4.3/KChiP3 Channels»
    Prieto A.; Cercos P.; de la Cruz A.; González T.; Gutierrez-Rodriguez M.; Naranjo J.R.; Valenzuela C. Biophys. J.2014106, p544a  (ir a revista)
  • «Enantioselective synthesis of PPAR agonists and antagonists»  P. Goya, R. Fernández, R. González-Muñiz, J. Elguero. Curr. Top. Med. Chem.201414, 1283-1293
  • «Clicked bis-PEG-peptide conjugates for studying calmodulin-Kv7.2 channel binding»
    Bonache, MA; Alaimo, A; Malo, C; Millet, O; Villarroel, A; Gonzalez-Muniz, R
    ORGANIC & BIOMOLECULAR CHEMISTRY201412, 8877-8887  (ir a revista)
  • «Chalcones as positive allosteric modulators of alpha 7 nicotinic acetylcholine receptors: A new target for a privileged structure»  Balsera, B; Mulet, J; Fernandez-Carvajal, A; de la Torre-Martinez, R; Ferrer-Montiel, A; Hernandez-Jimenez, JG; Estevez-Herrera, J; Borges, R; Freitas, AE; Lopez, MG; Garcia-Lopez, MT; Gonzalez-Muniz, R; de Vega, MJP; Valor, LM; Svobodova, L; Sala, S; Sala, F; Criado, M EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY201486, 724-739  (ir a revista)
  • «De Novo Designed Library of Linear Helical Peptides: An Exploratory Tool in the Discovery of Protein-Protein Interaction Modulators»  Bonache, MA; Balsera, B; Lopez-Mendez, B; Millet, O; Brancaccio, D; Gomez-Monterrey, I; Carotenuto, A; Pavone, LM; Reille-Seroussi, M; Gagey-Eilstein, N; Vidal, M; de la Torre-Martinez, R; Fernandez-Carvajal, A; Ferrer-Montiel, A; Garcia-Lopez, MT; Martin-Martinez, M; de Vega, MJP; Gonzalez-Muniz, R ACS COMBINATORIAL SCIENCE201416, 250-258  (ir a revista)
  • «Chameleonic reactivity of α-amino nitrile-derived ureas. Synthesis of highly functionalized imidazolidin-2-one and imidazolidine-2,4-dione derivatives»  Ventosa-Andres, P; Gonzalez-Vera, JA; García-Lopez, MT: Herranz, R Tetrahedron201455, 2142-2145
  • «Tetramic acids and indole derivatives from amino acid b-keto esters. Fine-tuning the conditions of the key Cu-catalyzed reaction»  Garcia-Aranda, MI; Garcia-Lopez, MT; de Vega, MJP; Gonzalez-Muniz, R Tetrahedron Lett.201455, 2142-2145  (ir a revista)
  • «Exploring the Phe-Gly Dipeptide-Derived Piperazinone Scaffold in the Search for Antagonists of the Thrombin Receptor PAR1.»  Valdivielso, AM; Garcia-Lopez, MT; Gutierrez-Rodriguez, M; Herranz, R Molecules (Basel, Switzerland)201419, 4814-46  (ir a revista)
  • «An Update on the Synthesis of β-Lactams»  M.T. Aranda, P. Pérez-Faginas, R. González-Muñiz. Advances in Organic Synthesis (eBook, Bentham)20136, 296-354
  • «Highly functionalized 2-oxopiperazine-based peptidomimetics: An approach to PAR1 antagonists»  Valdivielso, AM; Ventosa-Andres, P; Tato, F; Fernandez-Ibanez, MA; Pappos, I; Tsopanoglou, NE; Garcia-Lopez, MT; Gutierrez-Rodriguez, M; Herranz, R EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY201370, 199-224  (ir a revista)
  • «The Parkinson´s disease-associated GPR37 receptor-mediated cytotoxicity is controlled by its intracellular cysteine-rich domain»  Gandia, J; Fernandez-Duenas, V; Morato, X; Caltabiano, G; Gonzalez-Muniz, R; Pardo, L; Stagljar, I; Ciruela, F JOURNAL OF NEUROCHEMISTRY2013125,  362-372  (ir a revista)
  • «Helical peptides from VEGF and Vammin hotspots for modulating the VEGF-VEGFR interaction»  Garcia-Aranda, MI; Gonzalez-Lopez, S; Santiveri, CM; Gagey-Eilstein, N; Reille-Seroussi, M; Martin-Martinez, M; Inguimbert, N; Vidal, M; Garcia-Lopez, MT; Jimenez, MA; Gonzalez-Muniz, R; de Vega, MJP ORGANIC & BIOMOLECULAR CHEMISTRY201311, 1896-1905  (ir a revista)
  • «Solvent-Free Synthesis of alpha-Amino Nitrile-Derived Ureas»
    Ventosa-Andres, P; Gonzalez-Vera, JA; Garcia-Lopez, MT; Herranz, R
    ORGANIC LETTERS201315, 632-635  (ir a revista)
  • «Synthesis and Regioselective Functionalization of Piperazin-2-ones Based on Phe-Gly Pseudodipeptides»  Angel M. Valdivielso, Pilar Ventosa-Andrés, M. Teresa García-López, Rosario Herranz, and Marta Gutiérrez-Rodríguez Eur J Org Chem20131, 155-161  (ir a revista)
  • «Highly Functionalized 1,2-Diamino Compounds through Reductive Amination of Amino Acid-Derived beta-Keto Esters.»  Perez-Faginas, P; Aranda, M T; Garcia-Lopez, M T; Infantes, L; Fernandez-Carvajal, A; Gonzalez-Ros, J M; Ferrer-Montiel, A; Gonzalez-Muniz, R
    PloS one20138, e53231  (ir a revista)
  • «A study on the induction of stereoselectivity in the Strecker synthesis of basic amino acid-derived alpha-amino nitriles»  Ventosa-Andres, P; Garcia-Lopez, MT; Herranz, R
    Tetrahedron-Asymmetry201223, 15-16  (ir a revista)
  • «Advances in modulating thermosensory TRP channels»  Ferrer-Montiel, A; Fernandez-Carvajal, A; Planells-Cases, R; Fernandez-Ballester, G; Gonzalez-Ros, JM; Messeguer, A; Gonzalez-Muniz, R. Expert Oppinion on Therapeutic Patents201222, 999-1017  (ir a revista)
  • «Azepane Quaternary Amino Acids As Effective Inducers of 3(10) Helix Conformations»  Nunez-Villanueva, D; Infantes, L; Garcia-Lopez, MT; Gonzalez-Muniz, R; Martin-Martinez, M. Journal of Organic Chemistry201277, 9833-9839  (ir a revista)
  • «Design, synthesis and biological evaluation of new peptide-based ureas and thioureas as potential antagonists of the thrombin receptor PAR1.»  Ventosa-Andres, P; Valdivielso, A M; Pappos, I; Garcia-Lopez, M T; Tsopanoglou, N E; Herranz, R
    European Journal of Medicinal Chemistry201258, 98-111  (ir a revista)
  • «Discovery of new hits for TRPV1 blockade by high throughput assays»  Martinez, RD; Fernandez-Carvajal, A; Aranda, MT; Perez-Faginas, P; Bonache, MA; Gonzalez-Muniz, R; Ferrer-Montiel, A. Febs Journal2012279, 108-108   ISSN: 1742-464X
  • «Cyclic amino acid linkers stabilizing key loops of brain derived neurotrophic factor»
    Baeza, JL; de la Torre, BG ; Santiveri, CM; Almeida, RD; Garcia-Lopez, MT; Gerona-Navarro, G; Jaffrey, SR; Jimenez, MA; Andreu, D; Gonzalez-Muniz, R; Martin-Martinez, M
    Bioorganic & Medicinal Chemistry Letters201222, 444-448  (ir a revista)
  • «Optically active 1,3,4,4-tetrasubstituted beta-lactams: Synthesis and evaluation as tumor cell growth inhibitors»  Perez-Faginas, P; Aranda, MT; Garcia-Lopez, MT; Francesch, A; Cuevas, C; Gonzalez-Muniz, R EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY201146, 5108-5119  (ir a revista)
  • «Disulfide and amide-bridged cyclic peptide analogues of the VEGF(81-91) fragment: Synthesis, conformational analysis and biological evaluation»  Garcia-Aranda, MI; Mirassou, Y; Gautier, B; Martin-Martinez, M; Inguimbert, N; Vidal, M; Garcia-Lopez, MT; Jimenez, MA; Gonzalez-Muniz, R; de Vega, MJP
    BIOORGANIC & MEDICINAL CHEMISTRY201119, 7526-7533  (ir a revista)
  • «Synthesis and SAR studies on azetidine-containing dipeptides as HCMV inhibitors»
    Perez-Faginas, P; Aranda, MT; Garcia-Lopez, MT; Snoeck, R; Andrei, G; Balzarini, J; Gonzalez-Muniz, R. BIOORGANIC & MEDICINAL CHEMISTRY 201119, 1155-1161  (ir a revista)
  • «Parallel solid-phase synthesis of a small library of linear and hydrocarbon-bridged analogues of VEGF(81-91): Potential biological tools for studying the VEGF/VEGFR-1 interaction» Garcia-Aranda, MI; Marrero, P; Gautier, B; Martin-Martinez, M; Inguimbert, N; Vidal, M; Garcia-Lopez, MT; Jimenez, MA; Gonzalez-Muniz, R; de Vega, MJP
    BIOORGANIC & MEDICINAL CHEMISTRY201119, 1978-1986  (ir a revista)
  • «TRPV1 modulators: Structure-activity relationships using a rational combinatorial approach» Zaccaro, L; Garcia-Lopez, MT; Gonzalez-Muniz, R; Garcia-Martinez, C; Ferrer-Montiel, A; Albericio, F; Royo, M BIOORGANIC & MEDICINAL CHEMISTRY LETTERS201121, 3541-3545  (ir a revista)
  • «Helical peptides derived from the dimerization helix of the capsid protein of HIV-1bind protein wt. Domenech, R; Bocanegra, R; Gonzalez-Muniz, R; Gomez, J; Mateu, MG; Neira, JL
    EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS201140, 137-137   IDS Number: 804EO ISSN: 0175-7571
  • «Quaternary alpha,alpha-2-Oxoazepane alpha-Amino Acids: Synthesis from Ornithine-Derived beta-Lactams and Incorporation into Model Dipeptides»
    Nunez-Villanueva, D; Bonache, MA; Infantes, L; Garcia-Lopez, MT; Martin-Martinez, M; Gonzalez-Muniz, R. JOURNAL OF ORGANIC CHEMISTRY201176, 6592-6603  (ir a revista)
  • «A Role for Ring-Closing Metathesis in Medicinal Chemistry: Mimicking Secondary Architectures in Bioactive Peptides» de Vega, MJP; Garcia-Aranda, MI; Gonzalez-Muniz, R
    MEDICINAL RESEARCH REVIEWS201131, 677-715  (ir a revista)
  • «Larger Helical Populations in Peptides Derived from the Dimerization Helix of the Capsid Protein of HIV-1 Results in Peptide Binding toward Regions Other than the «Hotspot» Interface»  Domenech, R; Bocanegra, R; Gonzalez-Muniz, R; Gomez, J; Mateu, MG; Neira, JL
    BIOMACROMOLECULES201112, 3252-3264  (ir a revista)
  • «Solid-Phase Synthesis of a Library of Amphipatic Hydantoins. Discovery of New Hits for TRPV1 Blockade»  Gerona-Navarro, G; Gonzalez-Muniz, R; Fernandez-Carvajal, A; Gonzalez-Ros, JM; Ferrer-Montiel, A; Carreno, C; Albericio, F; Royo, M
    ACS COMBINATORIAL SCIENCE201113, 458-465  (ir a revista)
  • «Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers»  de Vega MJP, Garcia-Lopez MT, Zaccaro L, Royo M, Albericio F, Fernandez-Carvajal A, Ferrer-Montiel A, Gonzalez-Muniz R
    MOLECULES201015, 4924-4933  (ir a revista)
  • «2-Alkyl-2-carboxyazetidines as gamma-turn inducers: incorporation into neurotrophin fragments»  Baeza JL, Bonache MA, Garcia-Lopez MT, Gonzalez-Muniz R, Martin-Martinez M
    AMINO ACIDS201039, 1299-1307   (ir a revista)
  • «Induction Of A Gamma-Turn In 26rfa And 26rfa(20-26) by Insertion Of Azetidine-Derived Amino Acids»  Lefranc LB, Neveu C, Baeza JL, Gonzalez-Muniz R , Le Marec O , Guilhaudis L, Segalas-Milazzo I , Vaudry H, Martn-Martinez M, Leprince J
    JOURNAL OF PEPTIDE SCIENCE201016, 99-99   ISSN: 1075-2617.
  • «Thrombin-Activated Receptors: Promising Targets for Cancer Therapy?»  Garcia-Lopez MT, Gutierrez-Rodriguez M, Herranz R CURRENT MEDICINAL CHEMISTRY201017, 109-128   ISSN: 0929-8673.
  • «Further Evidence for 2-Alkyl-2-carboxyazetidines as γ-Turn Inducers»  J. L. Baeza, G. Gerona-Navarro, K. Thompson; M. J. Pérez de Vega, L. Infantes; M. T. García-López, R. González-Muñiz, M. Martín-Martínez. J. Org. Chem.200974, 8203-8211
  • «An update on the synthesis of ß–lactams.»  Aranda, M. T.; Pérez-Faginas, P.; González-Muñiz, R. Curr. Org. Synth20096, 325-341   (ir a revista)
  • «Disulfide bonds versus Trp…Trp pairs in non-regular ß-hairpins: NMR structure of Vammin loop 3-derived peptides as a case study.»  Mirasou, Y; Santiveri, C. M.; Pérez de Vega, M. J.; González-Muñiz, R.; Jiménez, M. J.  ChemBioChem200910, 902-910   (ir a revista)
  • «Diimine reduction of C=C double bonds: Scope and limitations of the application to solid-phase peptide synthesis.»  García-Aranda, M. I.; González-Muñiz, R.; García-López, M. T.; Pérez de Vega, M. J. Eur. J. Org. Chem. 20090, 4149-4157   (ir a revista)
  • «The N-terminal tripeptide of insulin-like growth factor-I protects against beta-amyloid-induced somatostatin depletion by calcium and glycogen synthase kinase 3 beta modulation.»  Burgos-Ramos, E.; Martos-Moreno, G. A.; López, M. G.; Herranz, R.; Aguado-Llera, D.; Egea, J.; Frechilla, D.; Cenarruzabeitia, E.; León, R.; Arilla-Ferreiro, E.; Argente, J.; Barrios, V J Neurochem. 2009109, 360-70   (ir a revista)
  •  «Improved synthesis of the PAR-1 thrombin receptor antagonist RWJ-58259.»
    Valdivielso, A. M.; García-López, M. T.; Herranz, R.  ARKIVOC20080, 287-294    (08-3630JP).
  • «Simple, highly enantioselective access to quaternary 1,3,4,4-Ttetrasubstituted ß-lactams from amino acids: A solid-phase approach,»  Pérez-Faginas, P.; Aranda, M. T.; Coady, L.; García-López, M. T. and González-Muñiz, R.  Adv. Synth. Catal. 2008350, 2279-2285   (ir a revista).
  •  «Synthesis and antitumoral evaluation of indole alkaloid analogues containing an hexahydropyrrolo[1´, 2´,3´:1, 9a, 9]imidazo[1, 2-a]indole skeleton.»
    Ventosa Andrés, P.; González-Vera, J. A.; Valdivielso, A. M.; García-López, M. T. and Herranz, R. Bioorg. Med. Chem. 200816, 9313-9322    PMID: 18818089
  • «Potential of amino acid derived alfa-amino nitriles for generating molecular diversity.»
    González-Vera, J. A.; García-López, M. T. and Herranz, R.  Mini-Rev. Org. Chem. 20085, 209-221   (ir a revista)
  • «Exploring the binding pocket for pyridopyrimidine ligands at the CCK1 receptor by molecular docking,»  Toumi-Maouche, A.; Maouche, B.; Taïri-Kellou, S.; El-Aoufi, S.; Martín-Martínez, M.; González-Muñiz, R.; Fourmy, D. and Maigret, M.
    J. Mol. Model 200814, 303–314    PMID: 18286312«Synthesis and biological properties of ß-turned Aß31-35 constrained analogues.»  Pérez de Vega, M. J.; Baeza, J. L.; García-López, M. T.; Vila-Perelló, M.; Jiménez-Castells, C.; Simón, A. M.; Frechilla, D.; Del Río, J.; Gutiérrez-Gallego, R.; Andreu, D. and González-Muñiz, R.
    Bioorg. Med. Chem. Lett. 200818, 2078-2082    PMID: 18262786.
  • «Azetidine-derived amino acids versus proline derivatives. Alternative trends in reverse turn inductions.»  Baeza, J. L., Gerona-Navarro, G., Pérez de Vega, M. J., García-López, M. T., González-Muñiz, R. and Martín-Martínez, M. J. Org. Chem. 200873, 1704-1715    PMID: 18217770.
  • «From theoretical calculations to the enantioselective synthesis of a 1,3,4-trisubstituted Gly-derived 2-azetidinone» Pérez-Faginas, P.; Alkorta, I.; García-López, M. T. and González-Muñiz, R.Tetrahedron Lett. 200849, 215-218   (ir a revista)
  • «A microarray strategy for mapping of Protein Tyrosine Phosphatase Substrate Specificity.» Köhn, M.; Gutierrez-Rodriguez, M.; Jonkheijm, P.; Wetzel, S.; Wacker, R.; Schröder, H.; Prinz, H.; Niemeyer, C.M.; Breinbauer, R.; Szedlacsek, S. E.; Waldmann, H.
    Angew. Chem. Int. Ed.,200746, 7700-7703   (ir a revista)
  • «Exploiting the Substrate Tolerance of Farnesyltransferase for Site-Selective Protein Derivatization.» Nguyen, U. T. T.; Cramer, J.; Gomis, J.; Reents, R.; Gutierrez-Rodriguez, M.; Goody, R. S.; Alexandrov, K.; Waldmann, H. ChemBioChem,20078, 408-423   (ir a revista)
  • «Modulation of protein-protein interactions by stabilizing/mimicking protein secondary structure elements.» Pérez de Vega, M. J.; Martín-Martínez, M.; González-Muñiz, R.
    Curr. Top. Med. Chem. 20077, 33-62    PMID: 17266595.
  • «Synthesis of indole alkaloid analogues containing the novel hexahydropyrrolo [10,20,30:1,9a,9]imidazo[1,2-a]indole skeleton by ring-closing reactions of tryptophan-derived alfa-amino nitriles.» González-Vera, J. A.; García-López, M. T. and Herranz, R.
    Tetrahedron200763, 9229-9234   (ir a revista)
  • «Strategies for the design of non peptide CCK1R agonist/antagonist ligands.»
    García-López, M. T.; González-Muñiz, R.; M.Martín-Martínez and R.Herranz
    Curr. Top. Med. Chem. 20077, 1180-1194    PMID: 17584140«Synthesis of indole alkaloid analogues: Novel domino stereoselective electrophile addition-cyclization of tryptophan-derived alfa-amino nitriles.»
    González-Vera, J. A.; García-López, M. T. and Herranz, R.
    J. Org. Chem. 200772, 5395-5398    PMDI: 17579457«2-Alkyl-2-carboxyazetidines as scaffolds for the induction of beta-turns.»  Baeza, J. L.; Gerona-Navarro, G.; Pérez de Vega, M. J.; García-López, M. T.; González-Muñiz, R. and Martín-Martínez, M.
    Tetrahedron Lett. 200748, 3689-3693   (ir a revista)
  • «Exceptional Stereoselectivity in the Synthesis of 1,3,4-Trisubstituted 4-Carboxy -ß-Lactam Derivatives from Amino Acids.» Pérez-Faginas, P.; O Reilly, F.; O Byrne, A.; García-Aparicio, C.; Martín-Martínez, M.; Pérez de Vega, M. J.; García-López, M. T. and González-Muñiz, R. Org. Lett. 20079, 1593-1597    PMID: 17381101
  • «Chiral 1,3,6-trisubstituted tetrahydropyrimidine-2,4-diones: A convenient stereoselective synthesis from aspartic acid derivatives.»  Patiño-Molina, R.; Cubero-Lajo, I.; Pérez de Vega, M. J.; García-López, M. T. and González-Muñiz, R.  Tetrahedron. Lett. 200748, 3613-3616   (ir a revista)
  • «Simple approach to highly functionalized tetrahydropyrimidine-2,4-diones from perhydropyrazino[1,2-f]pyrimidine-3,6,8-trione precursors»  Patiño-Molina R.; García-López, M. T.; Cenarruzabeitia, E.; Del Río, J. and González-Muñiz, R.
    Synthesis, 20070, 1047-1053   (ir a revista)
  • «Studies on the reduction and reductive alkylation of amino-acid derived spirocyclic 2,6-dioxopiperazines.» González-Vera, J. A.; Ventosa-Andrés, P.; Cassey, J.; García-López, M. T. and Herranz, R.  Tetrahedron,200763, 2675-2683  (ir a revista)
  • «Regioselective Base-promoted nucleophilic ring opening of spirocyclic 2,6-dioxopiperazines: Synthesis, of N-(1-carboxycyclohexyl)amino acid derivatives.»
    González-Vera, J. A.; García-López, M. T. and Herranz, R
    Eur. J. Org. Chem20070, 548-554   (ir a revista)
  • «A generic building block for C- and N-terminal protein-labeling and protein-immobilization.» Watzke, A.; Gutierrez-Rodriguez, M.; Köhn, M.; Wacker, R.; Schröder, H.; Breinbauer, R.; Kuhlmann, J.; Alexandrov, K.; Niemeyer, C. M.; Goody , R. S.; Waldmann, H..
    Bioorg. Med. Chem.200614, 6288-6306   (ir a revista)
  • «Site-Selective Protein-Immobilization by Staudinger Ligation.»
    Watzke, A.; Köhn, M.; Gutierrez-Rodriguez, M.; Wacker, R.; Schröder, H.; Breinbauer, R.; Kuhlmann, J.; Alexandrov, K.; Niemeyer, C. M.; Goody , R. S.; Waldmann, H.
    Angew. Chem. Int. Ed., 200645, 1408-1412   (ir a revista)
  • «ß-Lactams derived from phenylalanine and homologues: effects of the distance between the aromatic ring and the alfa-strogenic reactive center on the memory of chirality.»
    Bonache, M. A.; Cativiela, C.; García-Lopez, M. T. and González-Muñiz, R.
    Tetrahedron. Lett. 200647, 5883-5887   (ir a revista)
  • «The neuroprotective activity of GPE tripeptide analogues does not correlate with glutamate receptor binding affinity.»  Alonso de Diego, S. A.; Gutierrez-Rodriguez, M.; Pérez de Vega, M. J.; González-Muñiz, R.; Herranz, R.; Martín-Martínez, M.; Cenarruzabeitia, E.; Frechilla, D.; Del Río, J.; Jimeno, M. L. and García-López, M. T. Bioorg. Med. Chem. Lett. 200616, 3396-3400    PMDI: 16650992
  • «Old molecules for new receptors: Trp(Nps)dipeptide derivatives as vanilloid TRPV1 channel blockers.» Bonache, M. A.; García-Martínez, C.; García de Diego, L.; Carreño, C.; Pérez de Vega, M. J.; García-López, M. T.; Ferrer-Montiel, A. and González-Muñiz, R.
    ChemMedChem20061, 429-438    PMID: 16892378
  • «New (Gly-Pro-Glu) (GPE) analogues. Expedite solid-phase synthesis and biological activity.» Alonso de Diego, S. A.; Gutierrez-Rodriguez, M.; Pérez de Vega, M. J.; Casabona, D.; Cativiela, C.; González-Muñiz, R.; Herranz, R.; Martín-Martínez, M.; Cenarruzabeitia, E.; Frechilla, D.; Del Río, J.; Jimeno, M. L. and García-Lopez, M. T. Bioorg. Med. Chem. Lett. 200616, 1392-1396    PMID: 16321525
  • «Stereoselective synthesis of amino acid-derived ß-lactams. Experimental evidence for TADDOL as a memory of chirality enhancer.» Bonache, M. A.; López, P.; Martín-Martínez, M.; García-López, M.T.; Cativiela, C. and González-Muñiz, R. Tetrahedron200662, 130-138   (ir a revista)
  • «New TRPV1 targeting agents for pain management.» González-Muñiz, R.
    Drug Discov. Today 200510, 1704-1705    PII: S1359-6446(05)03677-9
  • «Conformationally constrained CCK4 analogues incorporating IBTM and BTD ß-turn mimetics» Martín-Martínez, M.; De la Figuera, N.; Latorre, M.; García-López, M. T.; Cenarruzabeitia, E.; Del Río, J. and González-Muñiz, R. J. Med. Chem. 200548, 7667-674    PMID: 16302807
  • «Novel domino cyclization of tryptophan-derived amino nitriles. Scope and stereoselectivity.» González-Vera, J. A.; García-López, M. T. and Herranz, R.  J. Org. Chem. 200570, 8971-8976    PMID: 16049195
  • «Combination of molecular modeling, site-directed mutagenesis and SAR studies to delineate the binding site of pyridopyrimidine antagonists of the human CCK1 receptor.»  Martín-Martínez, M.; Marty, A.; Jourdan, M.; Escrieut, C.; Archer, E.; González-Muñiz, R.; García-López, M. T.; Maigret, B.; Herranz, R. and Fourmy, D.  J. Med. Chem. 200548, 4842-4850   PMID: 16033264
  • «Analogues of the neuroprotective tripeptide Gly-Pro-Glu (GPE). Synthesis and structure-activity relationships.»  Alonso de Diego, S. A.; Muñoz, P.; González-Muñiz, R.; Herranz, R.; Martín-Martínez, M.; Cenarruzabeitia, E.; Frechilla, D.; Del Río, J.; Jimeno, M. L. and García-López, M.T. Bioorg. Med. Chem. Lett. 200515, 2279-2283    PMID: 15837309
  • «Molecular diversity via amino acid derived alfa-amino nitriles: Synthesis of spirocyclic 2,6-dioxopiperazine derivatives.»  González-Vera, J. A.; García-López, M. T. and Herranz, R.
    J. Org. Chem. 200570, 3660-3666    PMID: 15845004
  • «From 1-acyl- ß lactam human cytomegalovirus protease inhibitors to 1-benzyloxycarbonylazetidines with improved antiviral activity. A straightforward approach to covalent to noncovalent inhibitors.»  Gerona-Navarro, G.; Pérez de Vega, M. J.; García-López, M.T.; Andrei, G.; Snoeck, R.; Balzarini, J.; De Clercq, E. and González-Muñiz, R.
    J. Med. Chem. 200548, 2612-2621    PMID: 15801851
  • «Synthesis, conformational analysis and cytotoxicity of conformationally constrained Aplidine and Tamandarine A analogues incorporating a beta-turn mimetic.»
    Gutierrez-Rodríguez, M.; Martín-Martínez, M.; García-López, M. T.; Herranz, R.; Polanco, C.; Cuevas, F.; Rodríguez-Campos, I.; Manzanares, I.; Cárdenas, F.; Feliz, M.; Lloyd-Williams, P. and Giralt, E. J. Med. Chem. 200447, 5700-5712    PMID: 15509169
  • «Thiourea-based potent and selective HCMV inhibitors»
    González-Muñiz, R Drug Discov. Today 20049, 1081-1082    PII: S1359-6446(04)03264-7
  • «5-(Tryptophylamino)-1,3-dioxoperhydro[1,2-c]pyrimidine-based potent and selective CCK1 receptor antagonists: Reversal of CCK1 receptor subtype selectivity toward CCK2 receptors.» Muñoz-Ruiz, P.; García-López, M. T.; Cenarruzabeitia, E.; Del Río, J.; Dufresne, M.; Foucaud, M.; Fourmy, D. and Herranz, R
    J. Med. Chem. 200447, 5318-5329    PMID: 15456276
  • «Unprecedent stereospecific synthesis of a novel tetracyclic ring system, a hybrid of tetrahydropyrrolo[2,3-b]indole and tetrahydroimidazo[1,2-a]indole, via a domino reaction upon a tryptophan-derived amino nitrile.»  González-Vera, J. A.; García-López, M. T. and Herranz, R. Org. Lett. 20046, 2641-2644    PMID: 15281733
  • «Gly-Pro-Glu protects ß-amyloid-induced somatostatin depletion in the rat cortex»
    Aguado-Llera, D.; Martín-Martínez, M.; García-López, M. T.; Arilla-Ferreiro, E. and Barrios, V.
    NeuroReport200415, 1979-1982    PMID: 15305149
  • «Dipeptoids: From the chemical structure of the endogenous peptide to the design of peptidomimetics.» Martín-Martínez, M.; Patiño-Molina, R.; García-López, M.T. and González-Muñiz, R. Mini Reviews Med. Chem20044, 669-680    PMID: 15279601
  • «Pharmacological study of IQM-97,423, a potent and selective CCK1 antagonist with protective effect in acute pancreatitis.»  Latorre, M.; Bartolomé-Nebreda, J. M.; García-López, M.T.; González-Muñiz, R., Herranz, R.; Del Río, J. and Cenarruzabeitia, E.
    Pharmacology200472, 68-76    PMID: 15331911
  • «Improved synthesis of [4,4]spirolactam beta-turn mimetic as surrogate of the didemnin side chain dipeptide Pro-N-Me-D-Leu.»  Gutierrez-Rodríguez, M.; García-López, M. T. and Herranz, R.  Tetrahedron200460, 5177-5183   (ir a revista)
  • «Synthesis and anti-HCMV activity of 1-acyl-ß-lactams and 1-acylazetidines derived from phenylalanine.» Gerona-Navarro, G.; Pérez de Vega, M. J. ; García-López, M.T.; Andrei, G.; Snoeck, R.; Balzarini, J.; De Clercq, E. and González-Muñiz, R.  Bioorg. Med. Chem. Lett. 200414, 2253-2256    PMID: 15081019
  • «Simple access to novel azetidine-containing conformationally restricted amino acids by chemoselective reduction of beta-lactams.»  Gerona-Navarro, G.; Bonache, M. A.; Alias, M.; Pérez de Vega, M. J.; García-López, M. T.; López, P.; Cativiela, C. and González-Muñiz, R. Tetrahedron Lett200445, 2193-2196  (ir a revista) tetlet.2004.01.023