Cruzain Inhibitors

por | Ago 22, 2016 | Cruzain Inhibitors

Cruzain (Cruzipain, GP57/51) is a member of the papain C1 family of cystein proteinases. The T. cruzi enzyme consists of a catalytic moiety with high identity to cathepsins S and L. and a particular C-terminal domain (C-T) which is absent in all other CPs of the C1...