The endocannabinoid system is a complex organization that includes transmembrane receptors CB1 and CB2, their endogenous ligands (known as endocannabinoids), and their mechanisms of synthesis, transport and inactivation. The exogenous cannabinoid ligands, are those natural or synthetic structures which change in a positive (agonist) or negative (antagonist) way the cannabinoid receptors.
Endocannabinoid System
