An IQM-work on the cover of the Journal of Medicinal Chemistry

An IQM-work on the cover of the Journal of Medicinal Chemistry

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The work entitled “Novel N-Acetyl Bioisosteres of Melatonin: Melatonergic Receptor Pharmacology, Physicochemical Studies and Phenotypic Assessment of their Neurogenic Potential”, published in theJournal of Medicinal Chemistry 2015, 58, 4998-5014 by the team of Dr. Maria Isabel Rodriguez Franco, has received the honor of being the cover of this prestigious Scientific Journal. The work demonstrated that new bioisosteres of melatonin, developed by the Neurodrugs Group, stimulated differentiation of rat neural stem cells to a neuronal phenotype, in some cases to a higher extent than melatonin. These results are very interesting, since the regeneration of damaged CNS tissues by an accident (trauma, stroke, …) or neurodegenerative (Alzheimer, Parkinson, …) and psychiatric diseases (depression,…) could be a great advance in the field of Regenerative Medicine.

[box] Link to the scientific work[/box]
[box] Link to the journal cover [/box]


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