• Innovative approaches for the discovery and development of multi-target drugs with neurogenic and / or neuroprotective properties, acting at melatonin receptors, neurotransmitters, cannabinoids, secretases, the antioxidant system, etc.
• Creation and screening of an in-house library of compounds with privileged structures to act in the nervous system.
• Cheminformatics for Drug Discovery (Molecular Modelling, Docking studies, Artificial Neural Network, etc)
• Development of theoretical and experimental methods for the evaluation of biological and pharmacokinetic properties (eg, penetration into the CNS and oral absorption).
• Development of fluorescent probes for the visualization of membrane receptors.
• Development of new photoswitchable neurodrugs, whose biological activity can be finely controlled by irradiation with light at life-compatible wavelengths.